ADIPOQ 抗体 (AA 1-244)
Quick Overview for ADIPOQ 抗体 (AA 1-244) (ABIN7111358)
抗原
See all ADIPOQ 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-244
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原理
- ADIPOQ antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1-244aa
Immunogen: adiponectin, C1Q and collagen domain containing
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亚型
- IgG2a
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- ADIPOQ (Adiponectin (ADIPOQ))
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别名
- ADIPOQ
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背景
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Synonyms: Adiponectin|30 kDa adipocyte complement-related protein|Adipocyte complement-related 30 kDa protein (ACRP30)|Adipocyte, C1q and collagen domain-containing protein|Adipose most abundant gene transcript 1 protein (apM-1)|Gelatin-binding protein|ADIPOQ|ACDC|ACRP30|APM1|GBP28
Background: Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
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分子量
- 26 kDa
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基因ID
- 9370
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UniProt
- Q15848
抗原
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