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Adenylosuccinate Lyase 抗体

This anti-Adenylosuccinate Lyase antibody is a 兔 多克隆 antibody detecting Adenylosuccinate Lyase in WB, IHC, ELISA, IF 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7111349
发货至: 中国

Quick Overview for Adenylosuccinate Lyase 抗体 (ABIN7111349)

抗原

See all Adenylosuccinate Lyase (ADSL) 抗体
Adenylosuccinate Lyase (ADSL)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Adenylosuccinate Lyase antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    adenylosuccinate lyase

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:10-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    Adenylosuccinate Lyase (ADSL)

    别名

    Adenylosuccinate lyase

    背景

    Synonyms:Adenylosuccinase, adenylosuccinate lyase, ADSL, AMPS, ASASE, ASL Background:ADSL(adenylosuccinate lyase) is also named as AMPS, ASase, ASL and belongs to the lyase 1 family. It is an enzyme involved in 2 pathways of purine nucleotide metabolism and catalyzes cleavage of succinyl groups to yield fumarate(PMID:18524658). Defects in ADSL are the cause of adenylosuccinase deficiency(ADSL deficiency). In humans, mutations in ADSL lead to an inborn error of metabolism originally characterized by developmental delay, often with autistic features(PMID:20884265)..The ADSL enzymatic activity is reduced in lymphocytes and red blood cells of the patient with severe psychomotor retardation(PMID:9545543). It has 2 isoforms produced by alternative splicing.

    分子量

    55 kDa

    基因ID

    158

    UniProt

    P30566

    途径

    Ribonucleoside Biosynthetic Process
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