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Adenylosuccinate Lyase 抗体

The 兔 多克隆 anti-Adenylosuccinate Lyase antibody is suitable to detect Adenylosuccinate Lyase in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, ELISA, IF 和 FACS.
产品编号 ABIN7111349
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Adenylosuccinate Lyase 抗体 (ABIN7111349)

抗原

See all Adenylosuccinate Lyase (ADSL) 抗体
Adenylosuccinate Lyase (ADSL)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Adenylosuccinate Lyase antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
  • 原理

    ADSL antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    adenylosuccinate lyase

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:10-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    Adenylosuccinate Lyase (ADSL)

    别名

    ADSL

    背景

    Synonyms: Adenylosuccinate lyase (ADSL, ASL)|Adenylosuccinase (ASase)|ADSL|AMPS

    Background: ADSL(adenylosuccinate lyase) is also named as AMPS, ASase, ASL and belongs to the lyase 1 family. It is an enzyme involved in 2 pathways of purine nucleotide metabolism and catalyzes cleavage of succinyl groups to yield fumarate(PMID:18524658). Defects in ADSL are the cause of adenylosuccinase deficiency(ADSL deficiency). In humans, mutations in ADSL lead to an inborn error of metabolism originally characterized by developmental delay, often with autistic features(PMID:20884265)..The ADSL enzymatic activity is reduced in lymphocytes and red blood cells of the patient with severe psychomotor retardation(PMID:9545543). It has 2 isoforms produced by alternative splicing.

    分子量

    55 kDa

    基因ID

    158

    UniProt

    P30566

    途径

    Ribonucleoside Biosynthetic Process
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