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ADAR 抗体

This anti-ADAR antibody is a 兔 多克隆 antibody detecting ADAR in WB, IHC, ELISA, IF 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7111327
发货至: 中国

Quick Overview for ADAR 抗体 (ABIN7111327)

抗原

See all ADAR 抗体
ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

适用

  • 85
  • 28
  • 23
  • 2
  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 81
  • 5
  • 1

克隆类型

  • 73
  • 14
多克隆

标记

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  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
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  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This ADAR antibody is un-conjugated

应用范围

  • 57
  • 27
  • 27
  • 21
  • 20
  • 10
  • 9
  • 8
  • 8
  • 6
  • 3
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    adenosine deaminase, RNA-specific

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:50-1:200, IP: 1:200-1:1000, IF: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

    别名

    ADAR1

    背景

    Synonyms:ADAR, ADAR1, adenosine deaminase, RNA, DRADA, DSH, DSRAD, G1P1, IFI 4, IFI4, Interferon inducible protein 4, K88dsRBP, p136 Background:ADAR1 is also named as ADAR1, DSRAD, G1P1, IFI4. It convert selected adenosine residues into inosine in substrate RNAs containing a relatively short dsRNA region(PMID:15556947). The human ADAR1 gene specifies two size forms of RNA-specific adenosine deaminase, an interferon(IFN) inducible ?150 kDa protein and a constitutively expressed N-terminally truncated ?110 kDa protein, encoded by transcripts with alternative exon 1 structures that initiate from different promoters(PMID:11111054). It has 5 isoforms produced by alternative promoter usage and alternative splicing. Defects in ADAR are a cause of dyschromatosis symmetrical hereditaria(DSH).ADAR1 can form respective homodimers, and this association is essential for its enzymatic activities(PMID:17428802).

    分子量

    110 kDa

    基因ID

    103

    UniProt

    P55265

    途径

    Protein targeting to Nucleus
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