AP3B2 抗体
Quick Overview for AP3B2 抗体 (ABIN7111312)
抗原
See all AP3B2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- AP3B2 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- adaptor-related protein complex 3, beta 2 subunit
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:200-1:2000 IP: 1:200-1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- AP3B2 (Adaptor-Related Protein Complex 3, beta 2 Subunit (AP3B2))
-
别名
- AP3B2
-
背景
-
Synonyms: AP-3 complex subunit beta-2|Adaptor protein complex AP-3 subunit beta-2|Adaptor-related protein complex 3 subunit beta-2|Beta-3B-adaptin|Clathrin assembly protein complex 3 beta-2 large chain|Neuron-specific vesicle coat protein beta-NAP|AP3B2
Background: Subunit of non-clathrin-and clathrin-associated adaptor protein complex 3(AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network(TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
-
分子量
- 120-140 kDa
-
基因ID
- 8120
-
UniProt
- Q13367
抗原
-