ACOX1 抗体 (AA 1-270)
Quick Overview for ACOX1 抗体 (AA 1-270) (ABIN7111266)
抗原
See all ACOX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-270
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原理
- ACOX1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1-270aa
Immunogen: acyl-Coenzyme A oxidase 1, palmitoyl
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:100 - 1:200, IF: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))
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别名
- ACOX1
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背景
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Synonyms: Peroxisomal acyl-coenzyme A oxidase 1 (AOX)|Palmitoyl-CoA oxidase|Peroxisomal fatty acyl-CoA oxidase|Straight-chain acyl-CoA oxidase (SCOX)|Peroxisomal acyl-CoA oxidase 1, A chain|Peroxisomal acyl-CoA oxidase 1, B chain|Peroxisomal acyl-CoA oxidase 1, C chain|ACOX1|ACOX
Background: The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.It has 3 isoforms produced by alternative splicing with the molecular mass of 70-74 kDa and can be cleaved post-translationally into a 50- kDa and a 22- kDa subunit between Val468 and Ala469 (PMID: 10672038).
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分子量
- 74 kDa
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基因ID
- 51
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UniProt
- Q15067
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途径
- Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process
抗原
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