ACPP 抗体 (AA 27-373)
Quick Overview for ACPP 抗体 (AA 27-373) (ABIN7111188)
抗原
See all ACPP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 27-373
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原理
- ACP3 antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 27-373aa
Immunogen: acid phosphatase, prostate
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亚型
- IgG2a
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应用备注
- WB: 1:200-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- ACPP (Acid Phosphatase, Prostate (ACPP))
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别名
- ACP3
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背景
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Synonyms: Prostatic acid phosphatase (PAP)|5'-nucleotidase (5'-NT)|Acid phosphatase 3|Ecto-5'-nucleotidase|Protein tyrosine phosphatase ACP3|Thiamine monophosphatase (TMPase)|PAPf39|ACP3|ACPP
Background: A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions( pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion(DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.
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分子量
- 48 kDa
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基因ID
- 55
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UniProt
- P15309
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途径
- Synaptic Membrane, Ribonucleoside Biosynthetic Process
抗原
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