OAS2 抗体
Quick Overview for OAS2 抗体 (ABIN7111098)
抗原
See all OAS2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- OAS2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- 2'-5'-oligoadenylate synthetase 2, 69/71kDa
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亚型
- IgG
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anti-2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) (AA 11-346) antibody
OAS2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) (AA 11-346) antibodyOAS2 适用: 人 WB 宿主: 小鼠 Monoclonal C1 unconjugated
anti-2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) (AA 401-500) antibodyOAS2 适用: 小鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) (N-Term) antibodyOAS2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) (AA 357-371) antibodyVerified OAS2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) (Internal Region) antibodyVerified OAS2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) (AA 35-84) antibodyOAS2 适用: 人, Pig, 犬, 大鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) (AA 398-447) antibodyOAS2 适用: 人, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))
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别名
- OAS2
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背景
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Synonyms: 2'-5'-oligoadenylate synthase 2 ((2-5')oligo(A) synthase 2, 2-5A synthase 2)|p69 OAS / p71 OAS (p69OAS / p71OAS)|OAS2
Background: Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates(2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L(RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L.
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分子量
- 66-71 kDa
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基因ID
- 4939
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UniProt
- P29728
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途径
- Hepatitis C
抗原
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