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CD86 抗体 (AA 26-247) (Biotin)

This Biotin-conjugated 兔 单克隆 anti-CD86 antibody (Clone DM84) specifically detects CD86 in FACS 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7093029
发货至: 中国
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北京 101111
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Quick Overview for CD86 抗体 (AA 26-247) (Biotin) (ABIN7093029)

抗原

See all CD86 抗体
CD86

适用

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宿主

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克隆类型

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单克隆

标记

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This CD86 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS), ELISA

克隆位点

DM84
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    AA 26-247

    纯化方法

    Purified from cell culture supernatant by affinity chromatography

    免疫原

    Recombinant human B7-2 (Leu26-Pro247) (ABIN6961107) produced by using human HEK293 cells

    亚型

    IgG
  • 应用备注

    ELISA 1/5000-10000,Flow Cyt  1/100

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute with deionized water

    缓冲液

    50 % Glycerol, PBS, pH 7.4, 0.1 % BSA,0.1 % Procline 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    CD86

    别名

    B7-2

    背景

    Synonyms:CD86, B7-2, B70, CD28LG2, LAB72, MGC34413
    Description:This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

    分子量

    37.7kDa

    基因ID

    942

    UniProt

    P42081

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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