CD86 抗体 (AA 26-247)
Quick Overview for CD86 抗体 (AA 26-247) (ABIN7092885)
抗原
See all CD86 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 26-247
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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免疫原
- Recombinant human B7-2 (Leu26-Pro247) (ABIN6961107) produced by using human HEK293 cells
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亚型
- IgG
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应用备注
- ELISA 1/5000-10000,Flow Cyt 1/100
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute with deionized water
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- CD86
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别名
- B7-2
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背景
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Synonyms:CD86, B7-2, B70, CD28LG2, LAB72, MGC34413
Description:This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. -
分子量
- 37.7kDa
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基因ID
- 942
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UniProt
- P42081
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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