VTA1 抗体 (AA 221-306) (HRP)
Quick Overview for VTA1 抗体 (AA 221-306) (HRP) (ABIN7091819)
抗原
See all VTA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 221-306
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Cow,Sheep,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human LIP5
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亚型
- IgG
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应用备注
- IHC-P 1:200-400
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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- VTA1 (Vps20-Associated 1 Homolog (VTA1))
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别名
- LIP5
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背景
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Synonyms: C6orf55 Chromosome 6 open reading frame 55, Dopamine responsive protein DRG 1, Dopamine-responsive gene 1 protein, DRG 1, DRG-1, DRG1, Homolog of mouse SKD1 binding protein 1, HSPC228, LIP5, LYST interacting protein 5, LYST-interacting protein 5, My012, SBP1, SKD1 binding protein 1, SKD1-binding protein 1, Vacuolar protein sorting-associated protein VTA1 homolog, Vps20 associated 1 homolog (S. cerevisiae), VTA1, VTA1_HUMAN
Background: Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR. Involved in HIV-1 budding.
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基因ID
- 51534
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UniProt
- Q9NP79
抗原
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