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USP2 抗体 (AA 1-258)

This anti-USP2 antibody is a 小鼠 单克隆 antibody detecting USP2 in WB. Suitable for 人.
产品编号 ABIN7091801
发货至: 中国

Quick Overview for USP2 抗体 (AA 1-258) (ABIN7091801)

抗原

See all USP2 抗体
USP2 (Ubiquitin Specific Peptidase 2 (USP2))

适用

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宿主

  • 60
  • 3
小鼠

克隆类型

  • 62
  • 1
单克隆

标记

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This USP2 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

1738CT331-50-87
  • 抗原表位

    • 10
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    AA 1-258

    交叉反应

    Green Monkey, 人

    纯化方法

    Purified by Protein G.

    免疫原

    Recombinant human USP2 between 1-258 amino acids.

    亚型

    IgG1
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 浓度

    0.5 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    USP2 (Ubiquitin Specific Peptidase 2 (USP2))

    别名

    USP2

    背景

    Synonyms: Ubiquitin carboxyl-terminal hydrolase 2, 3.4.19.12, 41 kDa ubiquitin-specific protease, Deubiquitinating enzyme 2, Ubiquitin thioesterase 2, Ubiquitin-specific-processing protease 2, USP2, UBP41

    Background: This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

    基因ID

    9099

    UniProt

    O75604
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