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RBX1 抗体 (AA 1-108)

RBX1 适用: 人 WB 宿主: 小鼠 Monoclonal C8F22 unconjugated
产品编号 ABIN7091652
发货至: 中国
  • 抗原 See all RBX1 抗体
    RBX1 (Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1))
    抗原表位
    • 15
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-108
    适用
    • 42
    • 33
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 39
    • 3
    小鼠
    克隆类型
    • 39
    • 3
    单克隆
    标记
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RBX1 antibody is un-conjugated
    应用范围
    • 32
    • 13
    • 13
    • 8
    • 8
    • 7
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    Human,Mouse
    免疫原
    Recombinant human RBX1 between 1-108 amino acids.
    克隆位点
    C8F22
    Top Product
    Discover our top product RBX1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    限制
    仅限研究用
  • 浓度
    0.5 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    RBX1 (Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1))
    别名
    RBX1 (RBX1 产品)
    别名
    BA554C12.1 antibody, RNF75 antibody, ROC1 antibody, 1500002P15Rik antibody, AA517855 antibody, im:7137515 antibody, zgc:136444 antibody, RBX1 antibody, ATRBX1 antibody, F7C8.160 antibody, F7C8_160 antibody, HRT1 antibody, REGULATOR OF CULLINS-1 antibody, RING-BOX 1 antibody, RING-box 1 antibody, hop21 antibody, BEST:CK01110 antibody, CG16982 antibody, CK01110 antibody, Dmel\CG16982 antibody, EG:115C2.11 antibody, Rbx1 antibody, Rbx1/Roc antibody, Roc antibody, Roc1alpha antibody, anon-EST:Posey65 antibody, dRbx1 antibody, dRoc1 antibody, dRoc1a antibody, ring-box 1 antibody, ring-box 1, E3 ubiquitin protein ligase antibody, RING-box 1 antibody, RING-box protein 1 antibody, RING-box protein 1a antibody, Regulator of cullins 1a antibody, RBX1 antibody, Rbx1 antibody, rbx1 antibody, MGG_08844 antibody, LOC9308017 antibody, rbx-1 antibody, Roc1a antibody
    背景

    Synonyms: E3 ubiquitin-protein ligase RBX1, MGC13357, MGC1481, Protein ZYP, Rbx 1, Rbx1, RBX1_HUMAN, Regulator of Cullins 1, Ring box 1, RING box protein 1, RING finger protein 75, RING finger protein, RING-box protein 1, Ringbox protein 1, RNF 75, RNF75, ROC 1, ROC1, ZYP protein.

    Background: E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair. The functional specificity of the E3 ubiquitin-protein ligase complexes depends on the variable substrate recognition components. As a component of the CSA complex promotes the ubiquitination of ERCC6 resulting in proteasomal degradation. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme, like CDC34, to the complex and brings it into close proximity to the substrate. Probably also stimulates CDC34 autoubiquitination. May be required for histone H3 and histone H4 ubiquitination in response to ultraviolet and for subsequent DNA repair. Promotes the neddylation of CUL1, CUL2, CUL4 and CUL4 via its interaction with UBE2M. Involved in the ubiquitination of KEAP1, ENC1 and KLHL41.

    基因ID
    9978
    UniProt
    P62877
    途径
    Cell Division Cycle, M Phase, SARS-CoV-2 Protein Interactome
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