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RPE65 抗体

This anti-RPE65 antibody is a 兔 多克隆 antibody detecting RPE65 in WB 和 IHC (p). Suitable for 小鼠.
产品编号 ABIN7091644
发货至: 中国

Quick Overview for RPE65 抗体 (ABIN7091644)

抗原

See all RPE65 抗体
RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))

适用

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小鼠

宿主

  • 41
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  • 1

克隆类型

  • 30
  • 19
多克隆

标记

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This RPE65 antibody is un-conjugated

应用范围

  • 36
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 预测反应

    Mouse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from mouse RPE65

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))

    别名

    RPE65

    背景

    Synonyms: All-trans-retinyl-palmitate hydrolase, LCA 2, LCA2, Leber congenital amaurosis, mRPE 65, mRPE65, p63, rd 12, rd12, Retinal pigment epithelium specific 61 kDa protein, Retinal pigment epithelium specific 65 kDa protein, Retinal pigment epithelium specific protein, Retinal pigment epithelium specific protein 65 kDa, Retinal pigment epithelium-specific 65 kDa protein, Retinitis pigmentosa 20, Retinoid isomerohydrolase, RP 20, RP20, RPE 65, RPE65, RPE65_HUMAN, sRPE 65, sRPE65.

    Background: The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells. Retinal pigment epithelium-specific protein (RPE65) is a 65 kDa protein belonging to the _-carotene dioxygenase family. This protein is important in 11-cis retinal production as well as in visual pigment regeneration. RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated. The soluble form of the protein binds vitamin A. Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2.

    基因ID

    19892

    UniProt

    Q91ZQ5
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