RAB23 抗体
Quick Overview for RAB23 抗体 (ABIN7091627)
抗原
See all RAB23 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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预测反应
- Human,Mouse
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免疫原
- Recombinant human RAB23 (Fragment) (His-tagged).
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亚型
- IgG1
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IF() -
限制
- 仅限研究用
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- RAB23 (RAB23, Member RAS Oncogene Family (RAB23))
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别名
- RAB23
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背景
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Synonyms: DKFZp781H0695, HSPC137, MGC8900, Rab 23, RAB family small GTP binding protein RAB 23, RAB23, member RAS oncogene family, RAB23_HUMAN, Ras related protein Rab 23, Ras-related protein Rab-23.
Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes.
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基因ID
- 51715
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UniProt
- Q9ULC3
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途径
- Tube Formation
抗原
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