R-Spondin 3 抗体 (AA 22-100) (HRP)
Quick Overview for R-Spondin 3 抗体 (AA 22-100) (HRP) (ABIN7091622)
抗原
See all R-Spondin 3 (RSPO3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-100
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交叉反应
- 人
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预测反应
- Mouse,Rat,Dog,Cow,Pig,Horse,Cat,Rabbit,Guinea Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human RSPO3
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亚型
- IgG
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应用备注
- WB 1:300-5000
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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- R-Spondin 3 (RSPO3)
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别名
- RSPO3
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背景
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Synonyms: CRISTIN1, hPWTSR, hRspo3, Protein with TSP type-1 repeat, PWTSR, R-spondin 3 homolog, R-spondin-3 [Precursor], R-spondin-3, Roof plate specific spondin-3, Roof plate-specific spondin-3, RSPO3_HUMAN, Thrombospondin type I domain containing 2, Thrombospondin type-1 domain-containing protein 2, THSD2.
Background: Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway, possibly via a direct interaction with Wnt proteins, and in a Wnt-independent beta catenin pathway through a receptor signaling pathway that may not use frizzled/LRP receptors. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.
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基因ID
- 84870
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UniProt
- Q9BXY4
抗原
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