RHOBTB2 抗体 (AA 631-727)
Quick Overview for RHOBTB2 抗体 (AA 631-727) (ABIN706241)
抗原
See all RHOBTB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 631-727
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交叉反应
- 人
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预测反应
- Mouse,Rat,Cow,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DBC2
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- RHOBTB2 (rho-Related BTB Domain Containing 2 (RHOBTB2))
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别名
- DBC2
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背景
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Synonyms: DBC2, Rho-related BTB domain-containing protein 2, Deleted in breast cancer 2 gene protein, p83, RHOBTB2, KIAA0717
Background: DBC2 is a member of the recently identified RhoBTB family, which is part of the Rho GTPase family. DBC2 has been implicated as a tumor suppressor in breast and lung cancer. Studies have shown that DBC2 binds to the ubiquitin ligase scaffold Cul3, and that Cul3 regulates DBC2 protein levels by ubiquitinating DBC2 directly, leading to its degradation by the proteasome.
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基因ID
- 23221
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UniProt
- Q9BYZ6
抗原
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