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MAGED1 抗体 (AA 50-200)

This anti-MAGED1 antibody is a 小鼠 单克隆 antibody detecting MAGED1 in WB. Suitable for 人.
产品编号 ABIN7091377
发货至: 中国

Quick Overview for MAGED1 抗体 (AA 50-200) (ABIN7091377)

抗原

See all MAGED1 抗体
MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

适用

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宿主

  • 34
  • 6
  • 1
小鼠

克隆类型

  • 37
  • 4
单克隆

标记

  • 22
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This MAGED1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

C5D3
  • 抗原表位

    • 7
    • 4
    • 2
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    • 1
    • 1
    • 1
    • 1
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    AA 50-200

    预测反应

    Human

    免疫原

    KLH conjugated synthetic peptide derived from human MAGED1
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 浓度

    0.5 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

    别名

    MAGED1

    背景

    Synonyms: DLXIN 1, MAGD1_HUMAN, MAGE D1 antigen, MAGE tumor antigen CCF, MAGE-D1 antigen, Melanoma antigen family D 1, Melanoma associated antigen D1, Melanoma-associated antigen D1, Neurotrophin receptor interacting MAGE homolog, Neurotrophin receptor-interacting MAGE homolog, NRAGE, PP2250.

    Background: Involved in the apoptotic response after nerve growthfactor (NGF) binding in neuronal cells. Binds NGFR/p75NTR andantagonizes its association with NTRK1/TrkA, inhibits cell cycleprogression, and facilitates NGFR-mediated apoptosis. May act as aregulator of the function of DLX family members. May regulateTP53/p53 transcriptional activity and inhibit cell proliferation.Enhances TP53 phosphorylation and accumulation. May enhanceubiquitin ligase activity of RING-type zinc finger-containing E3ubiquitin-protein ligases. Proposed to act through recruitmentand/or stabilization of the Ubl-conjugating enzyme (E2) at theE3:substrate complex.

    基因ID

    9500

    UniProt

    Q9Y5V3

    途径

    Neurotrophin Signaling Pathway
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