MAGED1 抗体 (AA 50-200)
Quick Overview for MAGED1 抗体 (AA 50-200) (ABIN7091377)
抗原
See all MAGED1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 50-200
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预测反应
- Human
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免疫原
- KLH conjugated synthetic peptide derived from human MAGED1
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应用备注
- WB 1:300-5000
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限制
- 仅限研究用
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
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别名
- MAGED1
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背景
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Synonyms: DLXIN 1, MAGD1_HUMAN, MAGE D1 antigen, MAGE tumor antigen CCF, MAGE-D1 antigen, Melanoma antigen family D 1, Melanoma associated antigen D1, Melanoma-associated antigen D1, Neurotrophin receptor interacting MAGE homolog, Neurotrophin receptor-interacting MAGE homolog, NRAGE, PP2250.
Background: Involved in the apoptotic response after nerve growthfactor (NGF) binding in neuronal cells. Binds NGFR/p75NTR andantagonizes its association with NTRK1/TrkA, inhibits cell cycleprogression, and facilitates NGFR-mediated apoptosis. May act as aregulator of the function of DLX family members. May regulateTP53/p53 transcriptional activity and inhibit cell proliferation.Enhances TP53 phosphorylation and accumulation. May enhanceubiquitin ligase activity of RING-type zinc finger-containing E3ubiquitin-protein ligases. Proposed to act through recruitmentand/or stabilization of the Ubl-conjugating enzyme (E2) at theE3:substrate complex.
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基因ID
- 9500
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UniProt
- Q9Y5V3
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途径
- Neurotrophin Signaling Pathway
抗原
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