MBP 抗体 (AA 241-304) (Biotin)
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北京 101111
Quick Overview for MBP 抗体 (AA 241-304) (Biotin) (ABIN7091370)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 241-304
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- affinity Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human MBP
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亚型
- IgG
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anti-MBP (AA 69-85) antibody
适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-MBP (AA 1-197) antibody适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-MBP (AA 182-197), (C-Term) antibody适用: 人, 大鼠, 小鼠, Pig WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-MBP (pThr232) antibody适用: 人, 大鼠, 小鼠 ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-MBP antibody适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 10C12 unconjugated
anti-MBP antibody适用: 人 WB, IF 宿主: 小鼠 Monoclonal 408CT17-4-3 unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- MBP
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背景
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Synonyms: Myelin Basic Protein, Myelin basic protien, GDB, Golli MBP, Hemopoietic MBP, HMBPR, HUGO, MBP, MGC99675, MLD, Myelin A1 Protein, Myelin Deficient, Myelin Membrane Encephalitogenic Protein, SHI, Shiverer, SP, MBP_HUMAN .
Background: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
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基因ID
- 4155
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UniProt
- P02686
抗原
-
