DNMT3A 抗体
Quick Overview for DNMT3A 抗体 (ABIN7091044)
抗原
See all DNMT3A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
预测反应
- Human
-
免疫原
- Recombinant human Dnmt3a.
-
-
-
-
应用备注
- WB 1:300-5000
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
-
别名
- Dnmt3a
-
背景
-
Synonyms: DNA (cytosine 5 ) methyltransferase 3 alpha, DNA (cytosine 5) methyltransferase 3A, DNA cytosine methyltransferase 3A2, DNA methyltransferase 3a, DNA methyltransferase HsaIIIA, DNA MTase HsaI, DNA MTase HsaIIIA, DNMT 3a, DNMT, DNMT3A2, M HsaIIIA, M.HsaIIIA, MCMT, Methyl CpG binding domain protein 3a.
Background: Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZNF238. Can actively repress transcription through the recruitment of HDAC activity.
-
基因ID
- 1788
-
UniProt
- Q9Y6K1
抗原
-