CAMKK2 抗体
Quick Overview for CAMKK2 抗体 (ABIN7090801)
抗原
See all CAMKK2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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预测反应
- Human,Mouse
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免疫原
- Recombinant human CAMKK2.
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应用备注
- WB 1:300-5000
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限制
- 仅限研究用
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
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别名
- CAMKK2
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背景
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Synonyms: Calcium/calmodulin dependent protein kinase beta, Calcium/calmodulin dependent protein kinase kinase 2, Calcium/calmodulin dependent protein kinase kinase beta, CaM kinase kinase beta, CaM KK beta, CAMKK 2, CAMKK, CaMKK beta, CAMKK beta protein, CAMKKB.
Background: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals. Seems to be involved in hippocampal activation of CREB1. May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.
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基因ID
- 10645
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UniProt
- Q96RR4
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途径
- AMPK Signaling
抗原
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