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CD13 抗体

This anti-CD13 antibody is a 兔 单克隆 antibody detecting CD13 in FACS, WB, IF, IHC (p) 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7090742
发货至: 中国

Quick Overview for CD13 抗体 (ABIN7090742)

抗原

See all CD13 (ANPEP) 抗体
CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This CD13 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

克隆位点

C4F12
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CD13

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IF()
    ICC 1:100-500

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

    别名

    CD13

    背景

    Synonyms: ANPEN, Aminopeptidase N, Alanyl aminopeptidase, Alanyl membrane aminopeptidase, Aminopeptidase M, Aminopeptidase N, ANPEP, APN, CD 13, CD13 antigen, gp150, hAPN, Lap 1, Lap1, Alanyl (membrane) aminopeptidase, AMPN_HUMAN, AP M, AP N, AP-M, AP-N, CD13, LAP 1, LAP1, PEPN, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, p150.

    Background: Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. This membrane-bound zinc metalloprotease is known to serve as a receptor for the HCoV-229E alphacoronavirus as well as other non-human coronaviruses. This gene has also been shown to promote angiogenesis, tumor growth, and metastasis and defects in this gene are associated with various types of leukemia and lymphoma. [provided by RefSeq, Apr 2020]

    基因ID

    290

    UniProt

    P15144

    途径

    Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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