XRN1 抗体 (AA 1455-1706)
Quick Overview for XRN1 抗体 (AA 1455-1706) (ABIN7090717)
抗原
See all XRN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1455-1706
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交叉反应
- 人
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预测反应
- Mouse
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纯化方法
- Purified by Protein G.
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免疫原
- Recombinant human XRN1 between1455-1706 amino acids.
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亚型
- IgG1
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应用备注
- WB 1:300-5000
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限制
- 仅限研究用
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- XRN1 (5'-3' Exoribonuclease 1 (XRN1))
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别名
- XRN1
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背景
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Synonyms: XRN1_HUMAN, Dhm2, mXRN1, SEP1, Strand-exchange protein 1 homolog, 5'-3' exoribonuclease 1.
Background: Lamins are type V intermediate filament proteins and are grouped into constitutively expressed B-type lamins and developmentally regulated A-type lamins. Lamin-binding proteins in the nuclear lamina and the nuclear interior include several protein families and/or types of proteins in higher eukaryotes such as the inner nuclear membrane proteins, lamin B receptor, emerin, MANI, three isoforms of lamina-associated polypeptide 1 (LAP 1), and several isoforms of LAP 2. Up to six LAP 2 isoforms derive from a single gene by alternative splicing in mammals and various isoforms have been described in Xenopus. The best characterized LAP2 isoforms are the inner nuclear membrane protein LAP 2 beta and the nucleoplasmic protein LAP 2 alpha, which are identical in their N-terminal 187-amino acid constant region but differ in their C termini. LAP 2 alpha specifically interacts with A-type lamins within the nuclear interior as part of a detergent- and salt-resistant nucleoskeletal structure.
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基因ID
- 54464
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UniProt
- Q8IZH2
抗原
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