PDIA2 抗体 (AA 431-525)
Quick Overview for PDIA2 抗体 (AA 431-525) (ABIN705881)
抗原
See all PDIA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 431-525
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PDIA2
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亚型
- IgG
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anti-Protein Disulfide Isomerase Family A, Member 2 (PDIA2) (Internal Region) antibody
Verified PDIA2 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Family A, Member 2 (PDIA2) antibodyPDIA2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Family A, Member 2 (PDIA2) (AA 129-141) antibodyVerified PDIA2 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Family A, Member 2 (PDIA2) (AA 477-481) antibodyVerified PDIA2 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Family A, Member 2 (PDIA2) (AA 326-525) antibodyPDIA2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Family A, Member 2 (PDIA2) (AA 21-527) antibodyPDIA2 适用: 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Family A, Member 2 (PDIA2) antibodyPDIA2 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Family A, Member 2 (PDIA2) (C-Term) antibodyPDIA2 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Family A, Member 2 (PDIA2) (AA 111-160) antibodyPDIA2 适用: 人, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- PDIA2 (Protein Disulfide Isomerase Family A, Member 2 (PDIA2))
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别名
- PDIA2
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背景
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Synonyms: Pancreatic protein disulfide isomerase, PDA2, PDI, PDIA2, PDIP, Protein disulfide isomerase A2, Protein disulfide isomerase, Protein disulfide isomerase family A member 2, PDIA2_HUMAN.
Background: The three dimensional structure of many extracellular proteins is stabilized by the formation of disulphide bonds. Studies suggest that a microsomal enzyme known as Protein Disulphide Isomerase (PDI) is involved in disulphide-bond formation and isomerization, as well as the reduction of disulphide bonds in proteins. PDI, which catalyses disulphide interchange between thiols and protein dilsulphides, has also been referred to as thiol:protein-disulphide oxidoreductase and as glutathione:insulin transhydrogenase because of its role in reduction of disulphide bonds. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the carboxy-terminus of PDI and other soluble endoplasmic reticulum (ER) resident proteins including the 78 and 94 kDa glucose regulated proteins (GRP78 and GRP94 respectively). The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
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基因ID
- 64714
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途径
- Maintenance of Protein Location, Cell RedoxHomeostasis, Unfolded Protein Response
抗原
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