CHMP1A 抗体 (AA 51-150)
Quick Overview for CHMP1A 抗体 (AA 51-150) (ABIN705236)
抗原
See all CHMP1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CHMP1A
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亚型
- IgG
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anti-Charged Multivesicular Body Protein 1A (CHMP1A) (AA 1-196) antibody
CHMP1A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 1A (CHMP1A) antibodyCHMP1A 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 1A (CHMP1A) (AA 1-196) antibodyCHMP1A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 1A (CHMP1A) antibodyCHMP1A 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 1A (CHMP1A) (AA 1-196) antibodyCHMP1A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- CHMP1A (Charged Multivesicular Body Protein 1A (CHMP1A))
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别名
- CHMP1A
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背景
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Synonyms: PCH8, CHMP1, PRSM1, PCOLN3, VPS46A, VPS46-1, Charged multivesicular body protein 1a, Chromatin-modifying protein 1a, CHMP1a, Vacuolar protein sorting-associated protein 46-1, hVps46-1, KIAA0047
Background: Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. May also be involved in chromosome condensation. Targets the Polycomb group (PcG) protein BMI1/PCGF4 to regions of condensed chromatin. May play a role in stable cell cycle progression and in PcG gene silencing.
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基因ID
- 5119
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UniProt
- Q9HD42
抗原
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