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- 抗原 See all Myeloperoxidase (MPO) 抗体
- Myeloperoxidase (MPO)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Myeloperoxidase antibody is conjugated to FITC
- 应用范围
- 请咨询
- 产品特性
- The clone 8/9, a mouse monoclonal antibody selectively binds with myeloperoxidase (MPO), a glycoprotein present in the granules of myeloid cells. MPO is critical for an optimal oxygen-dependent microbicidal activity of myeloid cells. The MPO generally appears in the myeloblast stage of myeloid cell differentiation. It is the most common functional protein of myeloid cells and is involved in the process of inflammatory immune responses mediated by myeloid cells. The primary translation product of MPO undergoes glycosylation with the production of 89 kDa heme-free apopro-MPO form followed by incorporation of heme and conversion into the enzymatically active pro-MPO form. Subsequently, pro-MPO becomes targeted to azurophil granules where final processing occurs to produce mature dimeric MPO consisting of the 59-64 kDa MPO alpha-chain and the 14 kDa MPO beta-chain. MPO gene expression may serve as an additional marker for subclassification of acute leukemias and may be used to identify leukemic cells arrested at an early stage of the myeloid differentiation pathway.
- 纯化方法
- Purified
- 纯度
- >95 %
- 质量等级
- GMP Grade
- 克隆位点
- 8-9
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product MPO Primary Antibody
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anti-Myeloperoxidase (MPO) antibody
MPO 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Myeloperoxidase (MPO) (AA 134-263) antibodyMPO 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myeloperoxidase (MPO) antibodyMPO 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myeloperoxidase (MPO) (AA 646-745) antibodyMPO 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E11 unconjugated
anti-Myeloperoxidase (MPO) (AA 50-310) antibodyMPO 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myeloperoxidase (MPO) (AA 406-745) antibodyMPO 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myeloperoxidase (MPO) (AA 678-745) antibodyMPO 适用: 人, 小鼠, 大鼠 ELISA, FACS, ICC, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Myeloperoxidase (MPO) (AA 253-718) antibodyMPO 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myeloperoxidase (MPO) (C-Term) antibodyMPO 适用: 人, 小鼠, 大鼠, 兔 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myeloperoxidase (MPO) antibodyMPO 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-692M unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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- 抗原
- Myeloperoxidase (MPO)
- 别名
- MPO (MPO 产品)
- 别名
- mKIAA4033 antibody, MPO antibody, LOC100335032 antibody, POX2' antibody, XPOX2' antibody, mpo antibody, mpo-A antibody, pmr-1 antibody, pmr1 antibody, pox2 antibody, xpox2 antibody, myeloperoxidase antibody, myeloperoxidase L homeolog antibody, MPO antibody, Mpo antibody, LOC100335032 antibody, mpo.L antibody
- 背景
- The clone 8/9, a mouse monoclonal antibody selectively binds with myeloperoxidase (MPO), a glycoprotein present in the granules of myeloid cells. MPO is critical for an optimal oxygen-dependent microbicidal activity of myeloid cells. The MPO generally appears in the myeloblast stage of myeloid cell differentiation. It is the most common functional protein of myeloid cells and is involved in the process of inflammatory immune responses mediated by myeloid cells. The primary translation product of MPO undergoes glycosylation with the production of 89 kDa heme-free apopro-MPO form followed by incorporation of heme and conversion into the enzymatically active pro-MPO form. Subsequently, pro-MPO becomes targeted to azurophil granules where final processing occurs to produce mature dimeric MPO consisting of the 59-64 kDa MPO alpha-chain and the 14 kDa MPO beta-chain. MPO gene expression may serve as an additional marker for subclassification of acute leukemias and may be used to identify leukemic cells arrested at an early stage of the myeloid differentiation pathway.
- 基因ID
- 4353
- UniProt
- P05164
- 途径
- Chromatin Binding
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