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CD8 alpha 抗体 (mFluor™450)

This mFluor™450-conjugated 小鼠 单克隆 anti-CD8 alpha antibody (Clone SK1) specifically detects CD8 alpha in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7077484
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for CD8 alpha 抗体 (mFluor™450) (ABIN7077484)

抗原

See all CD8 alpha (CD8A) 抗体
CD8 alpha (CD8A) (CD8a Molecule (CD8A))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD8 alpha antibody is conjugated to mFluor™450

应用范围

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Flow Cytometry (FACS)

质量等级

GMP Grade

克隆位点

SK1
  • 原理

    CD8a mFluor450 Antibody

    交叉反应

    Baboon, Chimpanzee, Cynomolgus, Green Monkey, Macaca nemestrina, 猕猴, Sooty mangabey (Cercocebus atys)

    产品特性

    The clone SK1 specifically binds with a 32-34 kDa type I transmembrane glycoprotein of human cells commonly known as CD8a.  It is a member of immunoglobulin superfamily.  The CD8α forms either a homodimer (2 alpha chains) or a heterodimer with CD8β and is expressed on the surface of cytotoxic T cells, and sub-sets of NK cells, cortical thymocytes, and also on some dendritic cells. CD8 functions as a co-receptor for T cell receptor and specifically binds to class I MHC for antigen recognition and T cell activation. It has the cross-reactive binding affinity with the CD8 cell surface antigen expressing in several non-human primates, including Baboon, Chimpanzee, Cynomolgus and Rhesus.

    纯化方法

    Purified

    纯度

    >95 %

    免疫原

    Human peripheral blood T cells

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2-8°C, Conjugated antibodies should never be frozen.
  • 抗原

    CD8 alpha (CD8A) (CD8a Molecule (CD8A))

    别名

    CD8a

    基因ID

    925

    NCBI登录号

    NM_001768

    UniProt

    P01732

    途径

    TCR Signaling
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