CD8 alpha 抗体 (mFluor™510)
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- 抗原 See all CD8 alpha (CD8A) 抗体
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD8 alpha antibody is conjugated to mFluor™510
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应用范围
- Flow Cytometry (FACS)
- 原理
- CD8a mFluor500 Antibody
- 交叉反应
- Baboon, Chimpanzee, Cynomolgus, Green Monkey, Macaca nemestrina, 猕猴, Sooty mangabey (Cercocebus atys)
- 产品特性
- The clone SK1 specifically binds with a 32-34 kDa type I transmembrane glycoprotein of human cells commonly known as CD8a. It is a member of immunoglobulin superfamily. The CD8α forms either a homodimer (2 alpha chains) or a heterodimer with CD8β and is expressed on the surface of cytotoxic T cells, and sub-sets of NK cells, cortical thymocytes, and also on some dendritic cells. CD8 functions as a co-receptor for T cell receptor and specifically binds to class I MHC for antigen recognition and T cell activation. It has the cross-reactive binding affinity with the CD8 cell surface antigen expressing in several non-human primates, including Baboon, Chimpanzee, Cynomolgus and Rhesus.
- 纯化方法
- Purified
- 纯度
- >95 %
- 质量等级
- GMP Grade
- 免疫原
- Human peripheral blood T cells
- 克隆位点
- SK1
- 亚型
- IgG1, kappa
- Top Product
- Discover our top product CD8A Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- 抗原
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- 别名
- CD8a (CD8A 产品)
- 基因ID
- 925
- NCBI登录号
- NM_001768
- UniProt
- P01732
- 途径
- TCR Signaling
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