CD8 alpha 抗体 (APC-Cy7)
Quick Overview for CD8 alpha 抗体 (APC-Cy7) (ABIN7077478)
抗原
See all CD8 alpha (CD8A) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD8a APC-Cyanine7 Antibody
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交叉反应
- Baboon, Chimpanzee, Cynomolgus, Green Monkey, Macaca nemestrina, 猕猴, Sooty mangabey (Cercocebus atys)
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产品特性
- The clone SK1 specifically binds with a 32-34 kDa type I transmembrane glycoprotein of human cells commonly known as CD8a. It is a member of immunoglobulin superfamily. The CD8α forms either a homodimer (2 alpha chains) or a heterodimer with CD8β and is expressed on the surface of cytotoxic T cells, and sub-sets of NK cells, cortical thymocytes, and also on some dendritic cells. CD8 functions as a co-receptor for T cell receptor and specifically binds to class I MHC for antigen recognition and T cell activation. It has the cross-reactive binding affinity with the CD8 cell surface antigen expressing in several non-human primates, including Baboon, Chimpanzee, Cynomolgus and Rhesus.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- Human peripheral blood T cells
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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别名
- CD8a
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基因ID
- 925
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NCBI登录号
- NM_001768
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UniProt
- P01732
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途径
- TCR Signaling
抗原
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