PABP 抗体 (meArg455, meArg460) (Cy7)
Quick Overview for PABP 抗体 (meArg455, meArg460) (Cy7) (ABIN704837)
抗原
See all PABP (PABPC1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- meArg455, meArg460
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic metylpeptide derived from human PABP around metylation site of Arg455/Arg460
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亚型
- IgG
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anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) (AA 350-450) antibody
PABPC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) antibodyPABPC1 适用: 人, 兔, 小鸡, 非洲爪蟾, Hamster WB, ELISA, IF, IP, FACS, ICC 宿主: 小鼠 Monoclonal 10E10 unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) (meArg455), (meArg460) antibodyPABPC1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) (AA 1-636) antibodyPABPC1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) (AA 101-200) antibodyPABPC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) (AA 431-480) antibodyPABPC1 适用: 人, 小鼠, 大鼠, 兔, 小鸡, Cow, 犬, 豚鼠, 马, 绵羊, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) (AA 250-279) antibodyPABPC1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB20873 unconjugated
anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) (Middle Region) antibodyPABPC1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))
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别名
- Pabp
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背景
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Synonyms: PAB1, PABP, PABP1, PABPC2, PABPL1, Polyadenylate-binding protein 1, PABP-1, Poly(A)-binding protein 1, PABPC1
Background: Binds the poly(A) tail of mRNA, including that of its own transcript. May be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. Involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Involved in regulation of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons, for the recognition of premature termination codons (PTC) and initiation of NMD a competitive interaction between UPF1 and PABPC1 with the ribosome-bound release factors is proposed.
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基因ID
- 26986
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UniProt
- P11940
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途径
- SARS-CoV-2 Protein Interactome
抗原
-
