CD58 抗体 (iFluor™488)
Quick Overview for CD58 抗体 (iFluor™488) (ABIN7077353)
抗原
See all CD58 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD58 iFluor488 Antibody
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产品特性
- The clone TS2/9 recognizes a 45-70 kD cell surface protein, currently known as CD58. It is a member of the immunoglobulin superfamily previously known as lymphocyte function-associated antigen 3 (LFA-3). Both hematopoietic and non-hematopoietic cells including B and T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts express CD58. CD58 has two isoforms and is highly expressed on antigen specific memory T cells and as well as dendritic cells. The CD58 mediates cellular adhesion and participates in signal transduction when it binds to its ligand, the CD2 antigen. Cellular interactions regulated by the CD58/CD2 antigens are involved in the antigen-independent adhesion pathway and cytotoxic T lymphocyte (CTL) activity.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- Human cytolytic T cells
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD58
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别名
- CD58
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基因ID
- 965
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UniProt
- P19256
抗原
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