CD3 抗体 (FITC)
Quick Overview for CD3 抗体 (FITC) (ABIN7077124)
抗原
See all CD3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD3 FITC Antibody
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产品特性
- The monoclonal SK7 clone recognizes antigen CD3ε epsilon, a 20KDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The CD3 complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor - CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. CD3ε is expressed on T lymphocytes, NK-T cells, and to a varying degree in developing thymocytes. CD3 plays central roles in TCR signaling, T lymphocyte activation, and antigen recognition.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- Human Thymocytes
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD3
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别名
- CD3
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基因ID
- 916
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NCBI登录号
- NM_000733
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UniProt
- P07766
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途径
- TCR Signaling, Ubiquitin Proteasome Pathway
抗原
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