CD1a 抗体 (PE)
Quick Overview for CD1a 抗体 (PE) (ABIN7076789)
抗原
See all CD1a 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD1a PE Antibody
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产品特性
- The clone OKT6, a mouse monoclonal antibody selectively recognizes 49- kDa type I transmembrane glycoprotein non-covalently associated with β2-microglobulin known as CD1a. The CD1a glycoprotein has structural similarities to MHC class I molecule and plays important role in antigen-presenting mechanism to T-cell receptors present on NK T-cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation NK T-cells, CD1a has been implicated in thymic T cell development. CD1a has been used as a marker for DCs in a range of human tumors and the density of CD1a DC has been associated with clinical outcome in patients with lung, colon, gastric, nasopharyngeal, laryngeal and tongue carcinomas.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- Human acute lymphoblastic leukemia cells
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD1a
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别名
- CD1a
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基因ID
- 909
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UniProt
- P06126
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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