CD22 抗体 (APC-iFluor™700)
Quick Overview for CD22 抗体 (APC-iFluor™700) (ABIN7076451)
抗原
See all CD22 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
原理
- CD22 APC-iFluor700 Antibody
-
产品特性
- The clone MYG13 recognizes CD22 cell surface antigen, a 130-140 kDa protein. The expression of CD22 is primarily restricted to the normal and neoplastic B cells but does not express on other hematopoietic cells. The initiation of expression of CD22 starts in the cytoplasm of pro-B and pre-B cells. Although CD22 is not expressed by plasma cells, it is abundantly expressed by the follicular mantle and marginal zone B-cells. Being a member of the immunoglobulin superfamily, CD22 serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and leukocytes. The role of CD22 in the activation of B-cells is primarily associated with tyrosine kinases mediated signal transduction pathways.
-
纯化方法
- Purified
-
纯度
- >95 %
-
免疫原
- Human Raji Cells
-
亚型
- IgG1, kappa
-
-
-
-
应用备注
- FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
-
-
-