ZNF746 抗体
Quick Overview for ZNF746 抗体 (ABIN7076272)
抗原
See all ZNF746 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse PARIS
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anti-Zinc Finger Protein 746 (ZNF746) (Middle Region) antibody
ZNF746 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 746 (ZNF746) (AA 395-444) antibodyZNF746 适用: 人, 小鼠, 大鼠, Cow, 兔, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 746 (ZNF746) (N-Term) antibodyZNF746 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB (H) 1:500-1:1000, IHC/IF (M,R) 1:1500-1:3000/1:1500-1:3000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- ZNF746 (Zinc Finger Protein 746 (ZNF746))
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别名
- PARIS
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背景
- ZNF746, also named as PARIS, which belongs to the krueppel C2H2-type zinc-finger protein family. ZNF746 mainly localizes to the cytoplasm and probably translocates to the nucleus to repress selected genes. ZNF746 as a transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death. ZNF746 may act as a downstream effector of PRKN and contribute to neurodegeneration in Parkinson disease cases caused by defects in PRKN.
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分子量
- 100 kDa
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基因ID
- 69228
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NCBI登录号
- NP_001156947
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UniProt
- Q3U133
抗原
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