WDR81 抗体
This anti-WDR81 antibody is a 兔 多克隆 antibody detecting WDR81 in WB, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for WDR81 抗体 (ABIN7076221)
抗原
See all WDR81 抗体
WDR81
(WD Repeat Domain 81 (WDR81))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This WDR81 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse WDR81
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anti-WD Repeat Domain 81 (WDR81) (AA 360-600) antibody
WDR81 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB (H,M,R) 1:1000- 1:2000, IHC/IF (M,R) 1:700-1:1400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- WDR81 (WD Repeat Domain 81 (WDR81))
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别名
- WDR81
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背景
- This gene functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport. It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome. May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated protein aggregates. In this process, may regulate the interaction of SQSTM1 with ubiquitinated proteins and also recruit MAP1LC3C (By similarity). May also be involved in maintenance of normal mitochondrial structure and organization.
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分子量
- 65 kDa
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基因ID
- 192652
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NCBI登录号
- NP_620400
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UniProt
- Q5ND34
抗原
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