UNC13A/Munc13-1 抗体
Quick Overview for UNC13A/Munc13-1 抗体 (ABIN7076146)
抗原
See all UNC13A/Munc13-1 (UNC13A) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse Munc13-1
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应用备注
- WB (M,R) 1: 1000-1: 2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- UNC13A/Munc13-1 (UNC13A) (Unc-13 Homolog A (UNC13A))
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别名
- Munc13-1
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背景
- Unc-13 homolog A (C. elegans) is a protein that in humans is encoded by the UNC13A gene.. This gene encodes a member of the UNC13 family. UNC13A plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool. It is particularly important in most glutamatergic-mediated synapses but not GABA-mediated synapses. It plays a role in dendrite formation by melanocytes and in secretory granule priming in insulin secretion.
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分子量
- 194 kDa
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基因ID
- 382018
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NCBI登录号
- NP_001025044
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UniProt
- Q4KUS2
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途径
- Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
抗原
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