UAP1L1 抗体
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北京 101111
Quick Overview for UAP1L1 抗体 (ABIN7076143)
抗原
适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse UAP1L1
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应用备注
- WB (M) 1:2000- 1:4000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- UAP1L1 (UDP-N-Acteylglucosamine Pyrophosphorylase 1-Like 1 (UAP1L1))
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别名
- UAP1L1
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背景
- UAP1 is a 56KDa isoform which catalyzes the final step of UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis from fructose-6-phosphate. UDP-GlcNAc, the activated form of GlcNAc moiety is used as a key precursor in N-linked glycosylation and the glycosylphosphatidylinositol (GPI)-anchor of cellular proteins. Crystallization studies revealed UAP1 is composed of a large central core flanked by two smaller extra domains. The central main domain displays a alpha/beta structure resembling the Rossmann fold. Northern Blot analysis detected abundant expression of UAP1 in testis and sperm with a low expression in placenta, muscle and liver. It is implicated in antibody-mediated infertility in males.
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分子量
- 57 kDa
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基因ID
- 227620
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NCBI登录号
- NP_001028465
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UniProt
- Q3TW96
抗原
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