UBR5 抗体
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北京 101111
Quick Overview for UBR5 抗体 (ABIN7076102)
抗原
See all UBR5 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse EDD
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应用备注
- IHC/IF (M,R) 1:350-1:700
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- UBR5 (Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5))
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别名
- EDD
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背景
- UBR5, also named as ubiquitin protein ligase E3 component n-reconin5, is a HECT domain-containing protein as a myocardin-binding protein. UBR5 is highly conserved in metazoans, has unique structural features, and has been implicated in regulation of DNA damage response, metabolism, transcription, and apoptosis. Hence, UBR5 is a key regulator of cell signaling relevant to broad areas of cancer biology . The human UBR5 gene has 59 exons, encoding an approximately 10kb mRNA and >300 kDa protein with widespread expression in various cell types.
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基因ID
- 70790
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NCBI登录号
- NP_001074828
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UniProt
- Q80TP3
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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