TTL 抗体
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北京 101111
Quick Overview for TTL 抗体 (ABIN7076048)
抗原
See all TTL 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse TTL
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应用备注
- IHC/IF (M,R) 1:2000-1:4000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- TTL (Tubulin tyrosine Ligase (TTL))
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别名
- TTL
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背景
- Tubulin-tyrosine ligase (TTL) is the enzyme responsible for the reversible addition of a tyrosine residue at the carboxyl end of alpha-tubulin. TTL forms stable complexes with tubulin and inhibit tubulin polymerization. TTL is frequently suppressed during tumor progression with resulting accumulation of detyrosinated alpha-tubulin in tumor cells. TTL suppression in human cancers is associated with increased tumor aggressiveness.
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基因ID
- 69737
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NCBI登录号
- NP_081468
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UniProt
- P38585
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途径
- Regulation of Cell Size
抗原
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