TRIM26 抗体
Quick Overview for TRIM26 抗体 (ABIN7076014)
抗原
See all TRIM26 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse TRIM26
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应用备注
- WB (H,M,R) 1:1000-1:1500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "Tripartite motif containing 26 prevents steatohepatitis progression by suppressing C/EBPδ signalling activation." in: Nature communications, Vol. 14, Issue 1, pp. 6384, (2023) (PubMed).
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: "Tripartite motif containing 26 prevents steatohepatitis progression by suppressing C/EBPδ signalling activation." in: Nature communications, Vol. 14, Issue 1, pp. 6384, (2023) (PubMed).
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- TRIM26 (Tripartite Motif Containing 26 (TRIM26))
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别名
- TRIM26
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背景
- TRIM26 is a member of the tripartite motif (TRIM) protein family composed of more than 70 members in human. TRIM proteins share a similar characteristic structure, which includes a RING (R) domain, one or two B-boxes (B), and a coiled coil (CC) domain in the N-terminal and a domain in the C-terminal with variable structures. TRIM26 potentiates virus-triggered IRF3, NF-κB activation, IFN-β induction, and cellular antiviral responses. Further investigation suggests that TRIM26 plays an important role in the antiviral innate immune response by bridging TBK1 to NEMO and mediating TBK1 activation.
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分子量
- 63 kDa
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基因ID
- 22670
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NCBI登录号
- NP_001020770
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UniProt
- Q99PN3
抗原
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