TLS/FUS 抗体
This 兔 多克隆 antibody specifically detects TLS/FUS in IHC 和 IF. It exhibits reactivity toward 小鼠.
产品编号 ABIN7075919
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for TLS/FUS 抗体 (ABIN7075919)
抗原
TLS/FUS
适用
小鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Immunohistochemistry (IHC), Immunofluorescence (IF)
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse FUS
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anti-TLS/FUS (C-Term) antibody
适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TLS/FUS (2meArg216 (asymetric)), (2meArg218 (asymetric)) antibody适用: 人 WB, IP 宿主: 小鼠 Monoclonal 2B12 unconjugated
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应用备注
- IHC/IF (M) 1:800-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- TLS/FUS
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背景
- FUS (also named TLS and POMp75) belongs to the RRM TET family. FUS may play a role in the maintenance of genomic integrity, it binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. FUS is also an RNA-binding protein, and its links to neurodegenerative disease proffer the intriguing possibility that altered RNA metabolism or RNA processing may underlie or contribute to neuron degeneration. FUS may be a cause of angiomatoid fibrous histiocytoma (AFH) and is implicated in certain forms of amyotrophic lateral sclerosis (ALS) and frontotemporal dementias (FTDs) such as frontotemporal lobar dementia with ubiquitin inclusions (FTLD-U).
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基因ID
- 233908
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NCBI登录号
- NP_631888
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UniProt
- P56959
抗原
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