SYTL2 抗体
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北京 101111
Quick Overview for SYTL2 抗体 (ABIN7075797)
抗原
See all SYTL2 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse SYTL2/SLP2
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应用备注
- IHC/IF (H,M,R) 1:800-1:1600/1:600-1:1200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- SYTL2 (Synaptotagmin Like Protein 2 (SYTL2))
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别名
- SYTL2/SLP2
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背景
- Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine (PS) and phosphatidylinositol-4,5-bisphosphate (PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca(2+) while binding to PIP2 is Ca(2+) insensitive.
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基因ID
- 83671
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NCBI登录号
- NP_001035174
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UniProt
- Q99N50
抗原
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