SYT1 抗体
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北京 101111
Quick Overview for SYT1 抗体 (ABIN7075794)
抗原
See all SYT1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse SYT1
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应用备注
- WB (M,R) 1:500-1:1000, IHC/IF (H) 1:1000-1:4000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- SYT1 (Synaptotagmin I (SYT1))
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别名
- SYT1
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背景
- This protein calcium sensor that participates in triggering neurotransmitter release at the synapse . May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner, these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes.
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分子量
- 60 kDa
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基因ID
- 20979
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NCBI登录号
- NP_001239270
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UniProt
- P46096
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途径
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
抗原
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