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SUPT3H/SPT3 抗体

This anti-SUPT3H/SPT3 antibody is a 兔 多克隆 antibody detecting SUPT3H/SPT3 in WB, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7075767
发货至: 中国

Quick Overview for SUPT3H/SPT3 抗体 (ABIN7075767)

抗原

See all SUPT3H/SPT3 (SUPT3H) 抗体
SUPT3H/SPT3 (SUPT3H) (Suppressor of Ty 3 Homolog (SUPT3H))

适用

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人, 小鼠, 大鼠

宿主

  • 23
  • 2

克隆类型

  • 23
  • 2
多克隆

标记

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  • 2
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This SUPT3H/SPT3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 交叉反应

    小鼠, 大鼠

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein corresponding to Human SUPT3H
  • 应用备注

    WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:500-1:1500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4, 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    SUPT3H/SPT3 (SUPT3H) (Suppressor of Ty 3 Homolog (SUPT3H))

    别名

    SUPT3H

    背景

    The transcription of many RNA polymerase II-dependent genes requires Spt3, a member of the S. cerevisiae SAGA complex. Transcription from delta sequences, the long terminal repeats that flank yeast Ty elements, requires the yeast SPT3 gene. Spt3 and Spt20 work together to recruit TATA-box binding protein (TBP) to the core promoter allowing TBP to bind to SAGA-dependent promoters. Null mutations in the Spt3 gene cause defects in sporulation, diploid filamentous growth, and haploid invasive growth, indicating that Spt3 has an important role in both mating and development pathways in yeast. At the promoters of some genes including yeast HO, HIS3 and TRP3 genes, Spt3 inhibits binding of TBP, resulting in reduced transcription.

    分子量

    36 kDa

    基因ID

    8464

    UniProt

    O75486
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