STRADA 抗体
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北京 101111
Quick Overview for STRADA 抗体 (ABIN7075730)
抗原
See all STRADA 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse STRAD
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应用备注
- WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:600-1:1200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- STRADA (STE20-Related Kinase Adaptor alpha (STRADA))
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别名
- STRAD
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背景
- LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating the tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. LYK5-LKB1 interaction results in phosphorylation of LYK5 and enhanced autophosphorylation of LKB1.
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分子量
- 48 kDa
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基因ID
- 72149
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NCBI登录号
- NP_001239377
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UniProt
- Q3UUJ4
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途径
- AMPK Signaling
抗原
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