SMYD2A 抗体
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北京 101111
Quick Overview for SMYD2A 抗体 (ABIN7075581)
抗原
See all SMYD2A 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse SMYD2
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应用备注
- IHC/IF (M,R) 1:1000-1:4000/1:1000-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))
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别名
- KMT3C/SMYD2
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背景
- Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53.
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基因ID
- 226830
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NCBI登录号
- NP_081072
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UniProt
- Q8R5A0
抗原
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