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Sarcomeric alpha Actinin 抗体

The 兔 多克隆 anti-Sarcomeric alpha Actinin antibody (ABIN7075510) specifically detects Sarcomeric alpha Actinin in WB, IEM, IF 和 IHC. The antibody is reactive with 小鼠 和 大鼠 samples.
产品编号 ABIN7075510
发货至: 中国
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Quick Overview for Sarcomeric alpha Actinin 抗体 (ABIN7075510)

抗原

Sarcomeric alpha Actinin

适用

小鼠, 大鼠

宿主

克隆类型

多克隆

应用范围

Western Blotting (WB), Immunoelectron Microscopy (IEM), Immunofluorescence (IF), Immunohistochemistry (IHC)
  • 交叉反应

    大鼠

    纯化方法

    Affinity purification

    免疫原

    KLH conjugated Synthetic peptide corresponding to Mouse alpha Actinin 2
  • 应用备注

    WB (M,R) 1:2000, IHC/IF ,IEM (M,R) 1:500-1:1000/1:2000/1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4, 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    Sarcomeric alpha Actinin

    背景

    The primary function of alpha-actinin 2 is to crosslink filamentous actin molecules and titin molecules from adjoining sarcomeres at Z-discs, a function that is modulated by phospholipids. It is clear from studies by Hampton etal. that this crosslinking can assume a variety of conformations, with preferences for 60° and 120° angles. Alpha-actinin 2 also functions in docking signaling molecules at Z-discs, and additional studies have also implicated alpha-actinin 2 in the binding of cardiac ion channels, Kv1.5 in particular.

    分子量

    104 kDa

    基因ID

    11472

    NCBI登录号

    NP_150371

    UniProt

    Q9JI91
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