Sarcomeric alpha Actinin 抗体
适用: 小鼠, 大鼠
WB, IEM, IF, IHC
宿主: 兔
Polyclonal
unconjugated
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- 抗原
- Sarcomeric alpha Actinin
- 适用
- 小鼠, 大鼠
- 宿主
- 兔
- 克隆类型
- 多克隆
- 应用范围
- Western Blotting (WB), Immunoelectron Microscopy (IEM), Immunofluorescence (IF), Immunohistochemistry (IHC)
- 交叉反应
- 大鼠
- 纯化方法
- Affinity purification
- 免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse alpha Actinin 2
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- 应用备注
- WB (M,R) 1:2000, IHC/IF ,IEM (M,R) 1:500-1:1000/1:2000/1:50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- Sarcomeric alpha Actinin
- 背景
- The primary function of alpha-actinin 2 is to crosslink filamentous actin molecules and titin molecules from adjoining sarcomeres at Z-discs, a function that is modulated by phospholipids. It is clear from studies by Hampton etal. that this crosslinking can assume a variety of conformations, with preferences for 60° and 120° angles. Alpha-actinin 2 also functions in docking signaling molecules at Z-discs, and additional studies have also implicated alpha-actinin 2 in the binding of cardiac ion channels, Kv1.5 in particular.
- 分子量
- 104 kDa
- 基因ID
- 11472
- NCBI登录号
- NP_150371
- UniProt
- Q9JI91
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