S100A9 抗体
Our Local Distributor
北京 101111
Quick Overview for S100A9 抗体 (ABIN7075497)
抗原
See all S100A9 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 大鼠
-
纯化方法
- Affinity purification
-
免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse S100A9
-
-
-
-
应用备注
- WB (M,R) 1:300-1:800, IHC/IF (M,R) 1:1500-1:3000/1:750-1:1500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
-
- S100A9 (S100 Calcium Binding Protein A9 (S100A9))
-
别名
- S100A9
-
背景
- Calcium-binding protein. Has antimicrobial activity towards bacteria and fungi. Important for resistance to invasion by pathogenic bacteria. Up-regulates transcription of genes that are under the control of NF-kappa-B. Plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). Promotes tubulin polymerization when unphosphorylated. Promotes phagocyte migration and infiltration of granulocytes at sites of wounding. Plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1. Extracellular calprotectin binds to target cells and promotes apoptosis. Antimicrobial and proapoptotic activity is inhibited by zinc ions.
-
分子量
- 13 kDa
-
基因ID
- 20202
-
NCBI登录号
- NP_001268781
-
UniProt
- P31725
-
途径
- Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
抗原
-