RBM45 抗体
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北京 101111
Quick Overview for RBM45 抗体 (ABIN7075477)
抗原
See all RBM45 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse RB-1
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应用备注
- IHC/IF (M,R) 1:700-1:1400/1:500-1:2500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- RBM45 (RNA Binding Motif Protein 45 (RBM45))
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别名
- RB-1
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背景
- RB1 belongs to the retinoblastoma protein family. It is a key regulator of entry into cell division that acts as a tumor suppressor. RB1 acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. It is directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation.
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基因ID
- 19645
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NCBI登录号
- NP_033055
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UniProt
- P13405
抗原
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