RNF7 抗体
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北京 101111
Quick Overview for RNF7 抗体 (ABIN7075471)
抗原
See all RNF7 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse RNF7
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应用备注
- IHC/IF (H,M,R) 1:500-1:2000/1:500-1:3000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- RNF7 (Ring Finger Protein 7 (RNF7))
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别名
- RNF7
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背景
- The RNF7 is probable a component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.
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基因ID
- 19823
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NCBI登录号
- NP_001298064
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UniProt
- Q9WTZ1
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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